The importance of copy numbers in genetic diagnostics and research
Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.
MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.
Latest News
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Nov 27, 2025Our Products are IVDR-Certified!
We have successfully obtained our certification under the new In Vitro Diagnostic Regulation (IVDR; 2017/746)! The first batch of flagship products are already available on the market under the new IVDR, well in advance of the transition period deadline.
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Nov 27, 2025Holiday Closure & Shipping Information
MRC Holland will be closed from December 25, 2025 until January 1, 2026.
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Nov 12, 2025New Product: NXtec D024 KaryoProfiler — High-Throughput, High-Resolution Alternative to Traditional Karyotyping
We have launched NXtec D024 KaryoProfiler, our newest digitalMLPA™ assay designed for comprehensive molecular karyotyping across a wide range of applications.
Come and Meet Us
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Jan 21, 2026 - 10:00–14:00 CET
Virtual Workshop: MLPA Raw Data Evaluation and Troubleshooting
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Jan 28, 2026 - London, UK
Visit us at Festival of Genomics
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Feb 04, 2026 - 10:00–14:00 CET
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
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Mar 04, 2026 - Munich, Germany
Visit us at GfH
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Mar 10, 2026 - Baltimore, USA
Visit us at ACMG