The importance of copy numbers in genetic diagnostics and research
Copy number variants play a role in many genetic disorders. The fast, accurate and affordable detection of CNVs is essential for clinical genetic testing and research.
MRC Holland develops tools for the detection of DNA copy numbers and methylation patterns associated with disease. Our MLPA® technique is the gold standard in this field, and is used around the world to study hereditary disorders and tumours.
Latest News
-
Oct 09, 2026Important Updates for Beckman MLPA Users
Important updates for Beckman MLPA users relating to a new version of Coffalyser.Net with improved quality checks and the gradual phasing out of our Cy5-labelled primers. Read more.
-
Oct 09, 2026The Potential of EZtec-MS for Newborn Screening
A new publication by researchers at MRC Holland highlights the potential of EZtec-MS, a new variation of the digitalMLPA technology, for newborn screening purposes. Read more.
-
Oct 09, 2026Coming Soon: D038 Carrier Plus for Expanded Carrier Status Determination in Challenging Genomic Regions
Our digitalMLPA™ portfolio is about to receive an update with the upcoming launch of NXtec D038 Carrier Plus – the expanded version of our digitalMLPA assay for carrier status analysis. Read more.
Come and Meet Us
-
Nov 6, 2026 · 10:00–14:00 CET
Virtual Workshop: MLPA Raw Data Evaluation and Troubleshooting
-
Nov 10–14, 2026 · Seattle, USA
Visit us at AMP
-
Nov 20, 2026 · 10:00–14:00 CET
Virtual Workshop: MLPA Data Analysis and Quality Control with Coffalyser.Net
-
Jan 27–28, 2027 · London, UK
Visit us at Festival of Genomics