Determining Copy Number in Inherited Disorders by MLPA and Capillary Electrophoresis
In this webinar, we explain the principles of the MLPA technology and describe the lab workflow and data analysis of an MLPA experiment. In this context, we discuss the use of Applied Biosystems™ 3500 Dx Series Genetic Analyzers and how they can be a key tool in your search for clear answers regarding copy number and methylation status using MLPA. Then, we briefly discuss some of MRC Holland's most popular MLPA assays and their applications, from hereditary breast and ovarian cancer syndrome, to spinal muscular atrophy, Duchenne/Becker muscular dystrophy, and Prader Willi and Angelman syndromes.
Key information
Takeaways
- Understand what MLPA is, how it works, the workflow on the Applied Biosystems 3500Dx Genetic Analyzer, and benefits of using MLPA in your inherited disease testing and research.
- Learn the common applications of MLPA as well as the most commonly used SALSA MLPA assays from MRC Holland.
- Understand how MLPA is used in methylation analysis, how it works, the workflow on the Applied Biosystems 3500Dx Genetic Analyzer, and benefits of using MLPA in your cancer profiling.
- Learn the common applications of Methylation-Specific MLPA (MS-MLPA) as well as the most commonly used MS-MLPA assays from MRC Holland.
Video
Hosted by Today's Clinical Lab.
Sponsored by Thermo Fisher Scientific.
If you have any questions about the webinar, feel free to contact us.
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