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P306 SPG11

SALSA MLPA Probemix P306 SPG11 detects copy number variations in the SPG11 gene.

Specifications

Contents: 51 MLPA probes, including 40 probes for SPG11 (covering all exons).

Tissue: human genomic DNA.

Application: research on spastic paraplegia 11 (SPG11).

For research use only (RUO). Not for use in diagnostics.

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List Prices Documentation

Key related products

P165 HSP mix-1

Includes probes for ATL1 (SPG3A) and SPAST.

P211 HSP region

Includes probes for the SPAST region (15q11 region; LOC84661, SLC30A6, TUBGCP5, NIPA2 and NIPA1).

P213 HSP mix-2

Includes probes for REEP1 and SPG7.

View all

General information

The SALSA MLPA Probemix P306 SPG11 is a research use only (RUO) assay for the detection of deletions or duplications in the SPG11 gene, which is associated with Spastic Paraplegia 11 (SPG11).

Spastic Paraplegia 11 (SPG11) is a neurological disorder characterised by progressive spasticity and weakness of the lower limbs. Other features associated with the disorder are, amongst others, mild intellectual disability, peripheral neuropathy and increased reflexes in the upper limbs. SPG11 is inherited in an autosomal recessive manner. The majority of associated mutations in the SPG11 gene are single nucleotide variants, but large deletions have been described.

More information is available at https://www.ncbi.nlm.nih.gov/books/NBK1210/.

Regulatory status

SALSA MLPA Probemix P306 SPG11 is for research use only (RUO) in all territories.

Product documentation

Version B2

Other versions

Contact us for earlier versions.

List prices

Product

Item no.
Description
Technology
Price
P306-025R
SALSA MLPA Probemix P306 SPG11 – 25 rxn
MLPA
€ 286.00
P306-050R
SALSA MLPA Probemix P306 SPG11 – 50 rxn
MLPA
€ 560.00
P306-100R
SALSA MLPA Probemix P306 SPG11 – 100 rxn
MLPA
€ 1096.00

Required reagents

A general SALSA MLPA Reagent Kit is required for MLPA experiments (to be ordered separately).

Item no.
Description
Technology
Price
EK1-FAM
SALSA MLPA Reagent Kit – 100 rxn – FAM (6 vials)
MLPA MS-MLPA
€ 348.00
EK1-CY5
SALSA MLPA Reagent Kit – 100 rxn – Cy5 (6 vials)
MLPA MS-MLPA
€ 348.00
EK5-FAM
SALSA MLPA Reagent Kit – 500 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK5-CY5
SALSA MLPA Reagent Kit – 500 rxn – Cy5 (5×6 vials)
MLPA MS-MLPA
€ 1600.00
EK20-FAM
SALSA MLPA Reagent Kit – 2000 rxn – FAM (5×6 vials)
MLPA MS-MLPA
€ 6152.00

Price details & ordering

The prices above are list prices for direct orders from MRC Holland. Contact us for a quote that takes discounts and additional costs (such as shipping costs) into account. Different prices apply for orders through one of our sales partners; contact your local supplier for a quote.

More information about ordering & prices

Positive samples

Inclusion of a positive sample is usually not required, but can be useful for the analysis of your experiments. MRC Holland has very limited access to positive samples and cannot supply such samples. We recommend using positive samples from your own collection. Alternatively, you can use positive samples from an online biorepository, such as the Coriell Institute.

We have no information about specific commercially available positive samples that can be used with this product.

Resources

General MLPA resources

MLPA education

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